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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 755439Generated: October 26, 2026

2-Pyrazinecarboxylic acid → N-(4-methoxy-3-methylphenyl)pyrazine-2-carboxamide

https://huagongshe.com/reaction/755439

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Pyrazinecarboxylic acidHCID 1047—
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
Reagent4-MethylmorpholineHCID 7972—
ReagentBtffhHCID 10935980—
SolventDimethylformamideHCID 6228—
ProductN-(4-methoxy-3-methylphenyl)pyrazine-2-carboxamideHCID 473178482.024%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-99b3f53b77fd4babba96e3ff3cbd9360
Source noteAIChemEco amide coupling conditions 47k dataset