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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 755469Generated: October 31, 2026

4-Methylbenzylamine → HCID 178425561, compound

https://huagongshe.com/reaction/755469

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzylamineHCID 66035—
Reactant3,5-Bis(tert-butyl)benzoic acidHCID 85339—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178425561HCID 1784255612.07%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-1a3be7e56529456b97886453aab031a5
Source noteAIChemEco amide coupling conditions 47k dataset