HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Bicyclo(2.2.1)heptan-2-yl)acetyl chloride → 2-Bicyclo[2.2.1]hept-2-yl-N-[1-(3-cyclopentyl-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propyl]acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Bicyclo(2.2.1)heptan-2-yl)acetyl chloride | HCID 14622584 | — |
| Reactant | 6-(1-aminopropyl)-3-cyclopentyl-1,2,4-triazin-5(4H)-one | HCID 135594067 | — |
| Product | 2-Bicyclo[2.2.1]hept-2-yl-N-[1-(3-cyclopentyl-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propyl]acetamide | HCID 135752528 | — |
Reaction Steps
In analogy to the procedure for Example 36A, 150 mg (0.67 mmol) 6-(1-aminopropyl)-3-cyclopentyl-1,2,4-triazin-5(4H)-one, 130 mg (0.74 mmol) bicyclo[2.2.1]hept-2-ylacetyl chloride and proportionate amounts of the other reagents are used. The crude product is used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07087605B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-b15035c4ddf34d9198f23884b4aa81c0 |
| Source note | uspto-grants-2006_08 |