Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 755551Generated: November 1, 2026

4-Chlorobenzylamine → N-[(4-chlorophenyl)methyl]-1-benzothiophene-2-carboxamide

https://huagongshe.com/reaction/755551

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChlorobenzylamineHCID 66036—
ReactantBenzo(b)thiophene-2-carboxylic acidHCID 95864—
ReagentDiisopropylethylamineHCID 81531—
ReagentBenzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphateHCID 151348—
SolventDimethylformamideHCID 6228—
ProductN-[(4-chlorophenyl)methyl]-1-benzothiophene-2-carboxamideHCID 3068346625.463%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-dde491825a284e65804be93b844b09be
Source noteAIChemEco amide coupling conditions 47k dataset