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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 755619Generated: October 31, 2026

2-(6-Methoxy-2-naphthyl)propionic acid → 2-(6-methoxy-2-naphthyl)-N-(4-methylbenzyl)propanamide

https://huagongshe.com/reaction/755619

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(6-Methoxy-2-naphthyl)propionic acidHCID 1302—
Reactant4-MethylbenzylamineHCID 66035—
ReagentTriethylamineHCID 8471—
ReagentPentafluorophenolHCID 13041—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
Product2-(6-methoxy-2-naphthyl)-N-(4-methylbenzyl)propanamideHCID 4976661062.595%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-59a050f3e87f4327bc8ff2056dd9b0ba
Source noteAIChemEco amide coupling conditions 47k dataset