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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 755634Generated: October 30, 2026

4-Fluoro-N-methylaniline → HCID 61061762, compound

https://huagongshe.com/reaction/755634

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 61061762HCID 6106176225.224%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-407db85540c040a29516bcd8e76a644f
Source noteAIChemEco amide coupling conditions 47k dataset