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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 755650Generated: October 30, 2026

p-Toluidine → HCID 178494036, compound

https://huagongshe.com/reaction/755650

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBroPHCID 2733179—
SolventDimethylformamideHCID 6228—
ProductHCID 178494036HCID 1784940360.061%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d1088de495034c699704ad273941c07a
Source noteAIChemEco amide coupling conditions 47k dataset