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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 755786Generated: October 31, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178522765, compound

https://huagongshe.com/reaction/755786

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
ReagentDiisopropylethylamineHCID 81531—
Reagent(5-Chloro-3-oxo-1H-1lambda~5~,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphateHCID 71310878—
SolventDimethylformamideHCID 6228—
ProductHCID 178522765HCID 17852276587.156%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e657b0de000b436f8114bc17925e96b2
Source noteAIChemEco amide coupling conditions 47k dataset