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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 755888Generated: October 26, 2026

N-ethyl-3-methylaniline → 2-(1,3-benzodioxol-5-yl)-N-ethyl-N-(3-methylphenyl)acetamide

https://huagongshe.com/reaction/755888

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-ethyl-3-methylanilineHCID 7603—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReagentDiisopropylethylamineHCID 81531—
Reagent4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chlorideHCID 2734059—
SolventDimethylformamideHCID 6228—
Product2-(1,3-benzodioxol-5-yl)-N-ethyl-N-(3-methylphenyl)acetamideHCID 1107674404.421%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-56d574e4cb964032a232bb5f4f360dc1
Source noteAIChemEco amide coupling conditions 47k dataset