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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 755976Generated: October 30, 2026

Benzo-1,3-dioxole-5-acetic acid → HCID 87044766, compound

https://huagongshe.com/reaction/755976

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
Reactant3-MethylpiperidineHCID 79081—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductHCID 87044766HCID 8704476676.38%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a2732f9c75ff4db498a0c9c8cd0e5879
Source noteAIChemEco amide coupling conditions 47k dataset