HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Adamantanecarbonyl chloride → N-[1-(3-Cyclopentyl-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propyl]-1-adamantanecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Adamantanecarbonyl chloride | HCID 98915 | — |
| Reactant | 6-(1-aminopropyl)-3-cyclopentyl-1,2,4-triazin-5(4H)-one | HCID 135594067 | — |
| Product | N-[1-(3-Cyclopentyl-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propyl]-1-adamantanecarboxamide | HCID 135752600 | — |
Reaction Steps
In analogy to the procedure for Example 36A, 150 mg (0.67 mmol) 6-(1-aminopropyl)-3-cyclopentyl-1,2,4-triazin-5(4H)-one, 150 mg (0.74 mmol) 1-adamantanecarbonyl chloride and proportionate amounts of the other reagents are used. The crude product is used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07087605B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-2c41a0bf41f549ef9c4090cba41496dd |
| Source note | uspto-grants-2006_08 |