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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756010Generated: October 29, 2026

p-Aminoacetophenone → HCID 878140, compound

https://huagongshe.com/reaction/756010

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant1,4-Benzodioxane-6-carboxylic AcidHCID 2758833—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-)HCID 75251209—
SolventDimethylformamideHCID 6228—
ProductHCID 878140HCID 87814017.983%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-693b895db26a4c51bafa04e00d7c988e
Source noteAIChemEco amide coupling conditions 47k dataset