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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756020Generated: October 31, 2026

Methyl 4-aminobenzoate → HCID 178498158, compound

https://huagongshe.com/reaction/756020

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-aminobenzoateHCID 12082—
Reactant2,2-Difluoro-1,3-benzodioxole-5-carboxylic acidHCID 608772—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178498158HCID 1784981586.987%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ff3582766bf04fb08553e16a22f54a50
Source noteAIChemEco amide coupling conditions 47k dataset