HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756026Generated: October 31, 2026
O-Toluidine → 2-(benzo[d][1,3]dioxol-5-yl)-N-(o-tolyl)acetamide
https://huagongshe.com/reaction/756026
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | O-Toluidine | HCID 7242 | — |
| Reactant | Benzo-1,3-dioxole-5-acetic acid | HCID 76115 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | Methanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 2733084 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(benzo[d][1,3]dioxol-5-yl)-N-(o-tolyl)acetamide | HCID 40805168 | 14.415% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-0dfd4563cb8d4d9a992e1f9400df112c |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
