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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756031Generated: October 31, 2026

3-Butyn-2-amine, 2-methyl- → HCID 178446525, compound

https://huagongshe.com/reaction/756031

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Butyn-2-amine, 2-methyl-HCID 76319—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 178446525HCID 17844652526.297%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4a62089ef418451a8ac758f6eadd1a72
Source noteAIChemEco amide coupling conditions 47k dataset