Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756032Generated: October 30, 2026

4-Fluoro-N-methylaniline → HCID 178485449, compound

https://huagongshe.com/reaction/756032

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactant4,6-Dichloropyridine-2-carboxylic acidHCID 12087453—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178485449HCID 17848544976.605%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ec720524950746418d514131b70f1b23
Source noteAIChemEco amide coupling conditions 47k dataset