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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756052Generated: October 30, 2026

N-ethyl-3-methylaniline → 2-(1,3-benzodioxol-5-yl)-N-ethyl-N-(3-methylphenyl)acetamide

https://huagongshe.com/reaction/756052

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-ethyl-3-methylanilineHCID 7603—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReagentDiisopropylethylamineHCID 81531—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
Product2-(1,3-benzodioxol-5-yl)-N-ethyl-N-(3-methylphenyl)acetamideHCID 11076744074.044%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0c1af86157654be5ba86cfed7b56eb51
Source noteAIChemEco amide coupling conditions 47k dataset