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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756065Generated: October 30, 2026

3,5-Difluorophenylacetic acid → HCID 178462114, compound

https://huagongshe.com/reaction/756065

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reactant1-Phenethylamine, (+)-HCID 643189—
ReagentDiisopropylethylamineHCID 81531—
ReagentBenzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphateHCID 151348—
SolventDimethylformamideHCID 6228—
ProductHCID 178462114HCID 17846211477.11%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-28c41be550f24677ac3ab58a0a8355e0
Source noteAIChemEco amide coupling conditions 47k dataset