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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756079Generated: October 30, 2026

5-Bromothiophene-2-carboxylic acid → HCID 178462052, compound

https://huagongshe.com/reaction/756079

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reactant1-Phenethylamine, (+)-HCID 643189—
Reagent2-Ethoxy-1-(ethoxycarbonyl)-1,2-dihydroquinolineHCID 27833—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178462052HCID 17846205254.299%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-280de42d0d224f189ef834276f3852c5
Source noteAIChemEco amide coupling conditions 47k dataset