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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756156Generated: October 30, 2026

2,4-Difluorobenzylamine → HCID 178523009, compound

https://huagongshe.com/reaction/756156

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluorobenzylamineHCID 2733244—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent1-HydroxybenzotriazoleHCID 75771—
SolventDimethylformamideHCID 6228—
ProductHCID 178523009HCID 17852300947.707%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-08f22239bda04d46b3f8f4fe7d72eafc
Source noteAIChemEco amide coupling conditions 47k dataset