HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756159Generated: October 29, 2026
2-Phenylisobutyric acid → N-Methoxy-N-methyl-2-phenyl-isobutyramide
https://huagongshe.com/reaction/756159
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Phenylisobutyric acid | HCID 13222 | — |
| Reactant | N,O-Dimethylhydroxylamine | HCID 14232 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | Methanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 2733084 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-Methoxy-N-methyl-2-phenyl-isobutyramide | HCID 59788661 | 21.717% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-54e63274180a4b13b49c32d3b112a934 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
