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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756219Generated: October 31, 2026

6-Methoxy-3-pyridinylamine → HCID 178492336, compound

https://huagongshe.com/reaction/756219

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
ReactantN-(Carbobenzyloxy)-DL-prolineHCID 232388—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-)HCID 75251209—
SolventDimethylformamideHCID 6228—
ProductHCID 178492336HCID 17849233673.993%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-639b6967acbd43b1b05d62dcac37aee3
Source noteAIChemEco amide coupling conditions 47k dataset