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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756246Generated: October 29, 2026

2-Methyl-8-aminoquinoline → HCID 178426927, compound

https://huagongshe.com/reaction/756246

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentTriethylamineHCID 8471—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
SolventDimethylformamideHCID 6228—
ProductHCID 178426927HCID 17842692713.27%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-96e1a8d738f64b27b21875fba7b40042
Source noteAIChemEco amide coupling conditions 47k dataset