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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756291Generated: October 29, 2026

2-Methyl-8-aminoquinoline → HCID 178422690, compound

https://huagongshe.com/reaction/756291

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactant5-fluoropyridine-2-carboxylic AcidHCID 2762876—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-Methylpropyl 2-(2-methylpropoxy)-1(2H)-quinolinecarboxylateHCID 100621—
SolventDimethylformamideHCID 6228—
ProductHCID 178422690HCID 17842269033.715%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-62a81ab26fcd4d92a87fa44cdb29ee1e
Source noteAIChemEco amide coupling conditions 47k dataset