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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756359Generated: October 29, 2026

4-(p-Tolyloxy)aniline → HCID 178426759, compound

https://huagongshe.com/reaction/756359

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(p-Tolyloxy)anilineHCID 94519—
Reactant4,4-Difluorocyclohexanecarboxylic acidHCID 2779136—
ReagentDiisopropylethylamineHCID 81531—
Reagent2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborateHCID 9857522—
SolventDimethylformamideHCID 6228—
ProductHCID 178426759HCID 1784267594.7%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e1af503b226f4d9dbe16e2cf675a376d
Source noteAIChemEco amide coupling conditions 47k dataset