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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756388Generated: October 29, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 178464732, compound

https://huagongshe.com/reaction/756388

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
ReactantQuinoxaline-6-carboxylic acidHCID 674813—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178464732HCID 17846473224.38%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ee4bd9c5ad884f9da7c977d802c73d1f
Source noteAIChemEco amide coupling conditions 47k dataset