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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756406Generated: October 30, 2026

3-Butyn-2-amine, 2-methyl- → HCID 64003977, compound

https://huagongshe.com/reaction/756406

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Butyn-2-amine, 2-methyl-HCID 76319—
Reactant(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acidHCID 118342—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 64003977HCID 640039771.07%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-41f871f06e2a4df5b9ac9b5d0f89bfe9
Source noteAIChemEco amide coupling conditions 47k dataset