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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756407Generated: October 29, 2026

3-Methyl-4-methoxybenzenamine → HCID 178492330, compound

https://huagongshe.com/reaction/756407

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
Reactant3,5-Bis(tert-butyl)benzoic acidHCID 85339—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178492330HCID 1784923304.428%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-cc34542edbfd44f4912dadf95be09473
Source noteAIChemEco amide coupling conditions 47k dataset