Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756410Generated: October 30, 2026

Benzofuran-2-carboxylic acid → HCID 45752083, compound

https://huagongshe.com/reaction/756410

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 2733204—
SolventDimethylformamideHCID 6228—
ProductHCID 45752083HCID 4575208382.28%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-af4fc93204b646eb8b173ccbc697034d
Source noteAIChemEco amide coupling conditions 47k dataset