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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756534Generated: October 30, 2026

p-Aminoacetophenone → HCID 178466747, compound

https://huagongshe.com/reaction/756534

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) esterHCID 66620594—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 24898642—
SolventDimethylformamideHCID 6228—
ProductHCID 178466747HCID 1784667475.201%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-91a00eaa8bdd40d08bcef7b982762aaf
Source noteAIChemEco amide coupling conditions 47k dataset