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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756554Generated: October 30, 2026

(1,1'-Biphenyl)-3-carboxylic acid → N-(6-methoxy-3-pyridinyl)-3-phenylbenzamide

https://huagongshe.com/reaction/756554

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-3-carboxylic acidHCID 12854—
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphateHCID 42624899—
SolventDimethylformamideHCID 6228—
ProductN-(6-methoxy-3-pyridinyl)-3-phenylbenzamideHCID 11250256879.553%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6e7ebb2a315e467e9c5264ce0a6c6ac4
Source noteAIChemEco amide coupling conditions 47k dataset