HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 2-(4-Bromophenyl)-7-cyclopentyl-5-ethylimidazo[5,1-f][1,2,4]triazin-4(3H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | N-{1-[3-(4-Bromophenyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl]propyl}cyclopentanecarboxamide | HCID 135752686 | — |
| Product | 2-(4-Bromophenyl)-7-cyclopentyl-5-ethylimidazo[5,1-f][1,2,4]triazin-4(3H)-one | HCID 135752606 | — |
Reaction Steps
In analogy to the procedure for Example 1, 2.34 g (5.77 mmol) N-{1-[3-(4-bromophenyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl]propyl}cyclopentanecarboxamide, 4.43 g (28.9 mmol) phosphoric trichloride are stirred at reflux for 3 hours, proportionate amounts of the solvents are used.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07087605B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-51030bc0c1e8473286edfced07098f01 |
| Source note | uspto-grants-2006_08 |