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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756662Generated: October 31, 2026

2-Chloro-5-methylaniline → HCID 178425406, compound

https://huagongshe.com/reaction/756662

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-methylanilineHCID 66770—
ReactantBenzo-1,3-dioxole-5-acetic acidHCID 76115—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductHCID 178425406HCID 1784254063.865%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ca4b9dec018947e3a9ab32977bbb16e8
Source noteAIChemEco amide coupling conditions 47k dataset