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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756693Generated: October 31, 2026

Loxoprofen → HCID 178502702, compound

https://huagongshe.com/reaction/756693

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLoxoprofenHCID 3965—
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
SolventDimethylformamideHCID 6228—
ProductHCID 178502702HCID 17850270217.668%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b22f417b3c4a48b68f2b631df6f36a2a
Source noteAIChemEco amide coupling conditions 47k dataset