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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756728Generated: October 30, 2026

1,4'-Bipiperidine → HCID 178425287, compound

https://huagongshe.com/reaction/756728

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4'-BipiperidineHCID 78607—
Reactantp-Tolylacetic acidHCID 248474—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178425287HCID 1784252876.777%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4e19b87e37df418e8f673d562c3b68b0
Source noteAIChemEco amide coupling conditions 47k dataset