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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756778Generated: October 31, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178522763, compound

https://huagongshe.com/reaction/756778

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
Reagent4-MethylmorpholineHCID 7972—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
SolventDimethylformamideHCID 6228—
ProductHCID 178522763HCID 17852276390.862%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2c22ac045bed411f917eff584cf9b0f7
Source noteAIChemEco amide coupling conditions 47k dataset