HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl 5-benzoylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate → (hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)(phenyl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl 5-benzoylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate | HCID 71285668 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | (hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)(phenyl)methanone | HCID 58312740 | — |
Reaction Steps
tert-butyl 5-benzoylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate (100 mg) was dissolved in 10% TFA solution in CH2Cl2 (10 mL). The reaction was stirred at room temperature for 24 hours. After removal of solvents, the residue, (hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)(phenyl)methanone, was used in the further reactions without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08835454B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-fe45223192ee436fafefecb4c2ceabd6 |
| Source note | uspto-grants-2014_09 |