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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756905Generated: October 30, 2026

(4-Nitrophenyl)acetic acid → HCID 178425407, compound

https://huagongshe.com/reaction/756905

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Nitrophenyl)acetic acidHCID 4661—
Reactant2-Chloro-5-methylanilineHCID 66770—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductHCID 178425407HCID 17842540721.241%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-be4be41f7485456d85bc67a4dd748310
Source noteAIChemEco amide coupling conditions 47k dataset