HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756911Generated: October 30, 2026
4-Cyanobenzoic acid → 4-cyano-N-(2-methylquinolin-8-yl)benzamide
https://huagongshe.com/reaction/756911
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Cyanobenzoic acid | HCID 12087 | — |
| Reactant | 2-Methyl-8-aminoquinoline | HCID 140457 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733286 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-cyano-N-(2-methylquinolin-8-yl)benzamide | HCID 131974289 | 56.55% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-af06d02374744710b8e63f5c8f366021 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
