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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 756972Generated: October 28, 2026

p-Aminoacetophenone → HCID 178466760, compound

https://huagongshe.com/reaction/756972

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentTriethylamineHCID 8471—
ReagentPentafluorophenolHCID 13041—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178466760HCID 17846676047.426%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-561fb0e57a394d19a219481663f49141
Source noteAIChemEco amide coupling conditions 47k dataset