HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-((1SR,2RS,4RS)-7-azabicyclo[2.2.1]heptan-2-yl)isoquinolin-5-amine → 2-(5-(((1SR,2RS,4RS)-2-(isoquinolin-5-ylamino)-7-azabicyclo[2.2.1]heptan-7-yl)methyl)-2-methylphenoxy)ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-((1SR,2RS,4RS)-7-azabicyclo[2.2.1]heptan-2-yl)isoquinolin-5-amine | HCID 67234592 | — |
| Reactant | 3-(2-Hydroxyethoxy)-4-methylbenzaldehyde | HCID 86654428 | — |
| Product | 2-(5-(((1SR,2RS,4RS)-2-(isoquinolin-5-ylamino)-7-azabicyclo[2.2.1]heptan-7-yl)methyl)-2-methylphenoxy)ethanol | HCID 53247551 | — |
Reaction Steps
Reaction of Intermediate 29 with 3-(2-hydroxyethoxy)-4-methylbenzaldehyde affords the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08835457B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-94d2a299b9f9413cb412910a9563dacc |
| Source note | uspto-grants-2014_09 |