4-Methylbenzaldehyde → HCID 67233675, compound

HRID 75700Notes

Reaction equation

HRID 75700 reaction equation
[CH:1]12[CH2:7][C:4]([NH:8][C:9]3[CH:10]=[C:11]4[C:15](=[CH:16][CH:17]=3)[NH:14][N:13]=[CH:12]4)([CH2:5][CH2:6]1)[CH2:3][NH:2]2.[CH3:18][C:19]1[CH:26]=[CH:25][C:22]([CH:23]=O)=[CH:21][CH:20]=1>>[CH3:18][C:19]1[CH:26]=[CH:25][C:22]([CH2:23][N:2]2[CH2:3][C:4]3([NH:8][C:9]4[CH:10]=[C:11]5[C:15](=[CH:16][CH:17]=4)[NH:14][N:13]=[CH:12]5)[CH2:7][CH:1]2[CH2:6][CH2:5]3)=[CH:21][CH:20]=1

Participants

3

Reactant 2

HCID 77254-MethylbenzaldehydeHCID 672342982-Azabicyclo[2.2.1]heptan-4-amine, N-1H-indazol-5-yl-

Product 1

HCID 67233675HCID 67233675, compound

Procedure

Reaction of Intermediate 25 with 4-methylbenzaldehyde affords the title compound.

Sources & evidence

ORD record
ord-07d5dc774a9f416c884bf15e4374dc7b
Source dataset
uspto-grants-2014_09
Patent number
US08835457B2

Reaction notes

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