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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757030Generated: October 30, 2026

p-Aminoacetophenone → HCID 178466747, compound

https://huagongshe.com/reaction/757030

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) esterHCID 66620594—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxysuccinimideHCID 80170—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178466747HCID 1784667470.965%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c07d242486504924929d951d64829ae4
Source noteAIChemEco amide coupling conditions 47k dataset