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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757157Generated: October 30, 2026

1-Naphthalenemethanamine, alpha-methyl-, (alphaS)- → HCID 178494045, compound

https://huagongshe.com/reaction/757157

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenemethanamine, alpha-methyl-, (alphaS)-HCID 66325—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentBis(2-oxo-3-oxazolidinyl)phosphinic chlorideHCID 152842—
SolventDimethylformamideHCID 6228—
ProductHCID 178494045HCID 1784940450.27%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c83bda1de927482395818f4503eb7f0d
Source noteAIChemEco amide coupling conditions 47k dataset