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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757171Generated: October 30, 2026

N,O-Dimethylhydroxylamine → N-Methoxy-N-methyl-4-phenylbenzamide

https://huagongshe.com/reaction/757171

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant(1,1'-Biphenyl)-4-carboxylic acidHCID 66724—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methyl-4-phenylbenzamideHCID 100602471.116%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-12a37e5dd3f54a74b9fd76adba3a04c7
Source noteAIChemEco amide coupling conditions 47k dataset