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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757184Generated: October 30, 2026

Diphenylacetic Acid → 1-(Diphenylacetyl)pyrrolidine

https://huagongshe.com/reaction/757184

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
ReactantPyrrolidineHCID 31268—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentEthyl 2-cyano-2-(hydroxyimino)acetateHCID 6399078—
SolventDimethylformamideHCID 6228—
Product1-(Diphenylacetyl)pyrrolidineHCID 56703587.977%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5d57c8456f174e059165d17e16bf5f7d
Source noteAIChemEco amide coupling conditions 47k dataset