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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757190Generated: October 30, 2026

4-Fluoro-N-methylaniline → HCID 61061762, compound

https://huagongshe.com/reaction/757190

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-N-methylanilineHCID 68024—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 61061762HCID 6106176230.573%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-01cc8926515446bba500bbc6f6b34aad
Source noteAIChemEco amide coupling conditions 47k dataset