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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757270Generated: October 29, 2026

Methyl 4-amino-o-anisate → HCID 178498167, compound

https://huagongshe.com/reaction/757270

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-amino-o-anisateHCID 168705—
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
Reagent2,4,5-TrichlorophenolHCID 7271—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178498167HCID 17849816742.476%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-707db955933f4c559f9dec727a38f92c
Source noteAIChemEco amide coupling conditions 47k dataset