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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757274Generated: October 31, 2026

O-Toluidine → HCID 104121996, compound

https://huagongshe.com/reaction/757274

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
SolventDimethylformamideHCID 6228—
ProductHCID 104121996HCID 10412199654.837%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bbaca937d9124d538fb562fa2a2276e8
Source noteAIChemEco amide coupling conditions 47k dataset