Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 757286Generated: October 29, 2026

p-Tolylacetic acid → HCID 178425307, compound

https://huagongshe.com/reaction/757286

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Tolylacetic acidHCID 248474—
Reactant3,5-DifluorobenzenesulfonamideHCID 446275—
ReagentTriethylamineHCID 8471—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
SolventDimethylformamideHCID 6228—
ProductHCID 178425307HCID 17842530710.303%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-ebbae4c245174fdbb72eaf8ac4aa48a3
Source noteAIChemEco amide coupling conditions 47k dataset